C5AR1
C5AR1，即补体成分5a受体1，别名CD88。它是一种G蛋白偶联受体，主要在粒细胞、单核细胞、树突状细胞和髓源性抑制细胞（MDSC）以及肿瘤细胞上表达。C5AR1的作用机制是通过与补体激活片段C5a结合，激活下游的G蛋白和β-抑制素信号通路，从而在先天性免疫反应中发挥关键作用。C5a-C5aR1轴的功能障碍与许多炎症和免疫介导的疾病有关，包括肿瘤的发生发展。C5AR1不仅参与免疫细胞的激活和趋化，还与肿瘤微环境的免疫调节有关，其表达水平在多种肿瘤中升高，可预测疾病进展和预后的生物标志物，以及潜在的治疗靶点。
热销产品
Recombinant Human C5a anaphylatoxin chemotactic receptor 1 (C5AR1)-VLPs (Active) (CSB-MP003996HU)
验证数据
CSB-MP003996HU is detected by Mouse anti-6*His monoclonal antibody.
Activity
Measured by its binding ability in a functional ELISA. Immobilized human C5AR1 at 10 μg/ml can bind Anti-C5AR1 recombinant antibody (CSB-RA003996A0HU), the EC50 is 1.239-3.760 ng/mL.
The presence of VLP-like structures was confirmed by TEM
C5AR1 Recombinant Monoclonal Antibody (CSB-RA003996A0HU)
验证数据
The Binding Activity of Human C5AR1-VLPs with Anti-C5AR1 recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human C5AR1 (CSB-MP003996HU) at 10 μg/mL can bind Anti-C5AR1 recombinant antibody, the EC50 is 1.239-3.760 ng/mL.
C5AR1 Antibodies
C5AR1 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA003996GA01HU | C5AR1 Antibody | Human,Mouse,Rat | ELISA,WB,IF |
| CSB-PA001479 | C5AR1 Antibody | Human | WB, IHC, IF, ELISA |
| CSB-PA060025 | Phospho-C5AR1 (S338) Antibody | Human | IHC, ELISA |
| CSB-PA003996LA01HU | C5AR1 Antibody | Human | ELISA, WB, IHC |
| CSB-RA003996A0HU | C5AR1 Recombinant Monoclonal Antibody | Human | ELISA |
C5AR1 Proteins
C5AR1 Proteins for Macaca mulatta (Rhesus macaque)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP003996MOW1 CSB-EP003996MOW1 CSB-BP003996MOW1 CSB-MP003996MOW1 CSB-EP003996MOW1-B |
Recombinant Macaca mulatta (Rhesus macaque) C5a anaphylatoxin chemotactic receptor (C5AR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF003996MOW | Recombinant Macaca mulatta (Rhesus macaque) C5a anaphylatoxin chemotactic receptor (C5AR1) | in vitro E.coli expression system |
C5AR1 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP003996HU1 CSB-BP003996HU1 CSB-MP003996HU1 |
Recombinant Human C5a anaphylatoxin chemotactic receptor (C5AR1), partial | Yeast Baculovirus Mammalian cell |
| CSB-CF003996HUd7 | Recombinant Human C5a anaphylatoxin chemotactic receptor 1 (C5AR1) | in vitro E.coli expression system |
| CSB-MP003996HU | Recombinant Human C5a anaphylatoxin chemotactic receptor 1 (C5AR1)-VLPs (Active) | Mammalian cell |
| CSB-EP003996HU1 | Recombinant Human C5a anaphylatoxin chemotactic receptor (C5AR1), partial | E.coli |
| CSB-EP003996HU1-B | Recombinant Human C5a anaphylatoxin chemotactic receptor (C5AR1), partial,Biotinylated | E.coli |
C5AR1 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP003996DO1 CSB-EP003996DO1 CSB-BP003996DO1 CSB-MP003996DO1 CSB-EP003996DO1-B |
Recombinant Dog C5a anaphylatoxin chemotactic receptor 1 (C5AR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF003996DO | Recombinant Dog C5a anaphylatoxin chemotactic receptor 1 (C5AR1) | in vitro E.coli expression system |
C5AR1 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP003996MO1 CSB-BP003996MO1 CSB-MP003996MO1 |
Recombinant Mouse C5a anaphylatoxin chemotactic receptor (C5ar1), partial | Yeast Baculovirus Mammalian cell |
| CSB-CF003996MO | Recombinant Mouse C5a anaphylatoxin chemotactic receptor (C5ar1) | in vitro E.coli expression system |
C5AR1 Proteins for Cavia porcellus (Guinea pig)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP003996GU1 CSB-EP003996GU1 CSB-BP003996GU1 CSB-MP003996GU1 CSB-EP003996GU1-B |
Recombinant Guinea pig C5a anaphylatoxin chemotactic receptor 1 (C5AR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF003996GU | Recombinant Guinea pig C5a anaphylatoxin chemotactic receptor 1 (C5AR1) | in vitro E.coli expression system |
C5AR1 Proteins for Pongo pygmaeus (Bornean orangutan)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP003996EXP1 CSB-EP003996EXP1 CSB-BP003996EXP1 CSB-MP003996EXP1 CSB-EP003996EXP1-B |
Recombinant Pongo pygmaeus C5a anaphylatoxin chemotactic receptor (C5AR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF003996EXP | Recombinant Pongo pygmaeus C5a anaphylatoxin chemotactic receptor (C5AR1) | in vitro E.coli expression system |
C5AR1 Proteins for Gorilla gorilla gorilla (Lowland gorilla)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP003996GGZ1 CSB-EP003996GGZ1 CSB-BP003996GGZ1 CSB-MP003996GGZ1 CSB-EP003996GGZ1-B |
Recombinant Gorilla gorilla gorilla C5a anaphylatoxin chemotactic receptor (C5AR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF003996GGZ | Recombinant Gorilla gorilla gorilla C5a anaphylatoxin chemotactic receptor (C5AR1) | in vitro E.coli expression system |
C5AR1 Proteins for Pan troglodytes (Chimpanzee)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP003996EQV1 CSB-EP003996EQV1 CSB-BP003996EQV1 CSB-MP003996EQV1 CSB-EP003996EQV1-B |
Recombinant Pan troglodytes C5a anaphylatoxin chemotactic receptor (C5AR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF003996EQV | Recombinant Pan troglodytes C5a anaphylatoxin chemotactic receptor (C5AR1) | in vitro E.coli expression system |
C5AR1 Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP003996RA1 CSB-EP003996RA1 CSB-BP003996RA1 CSB-MP003996RA1 CSB-EP003996RA1-B |
Recombinant Rat C5a anaphylatoxin chemotactic receptor (C5ar1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF003996RA | Recombinant Rat C5a anaphylatoxin chemotactic receptor (C5ar1) | in vitro E.coli expression system |
C5AR1 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP003996DIL1 CSB-EP003996DIL1 CSB-BP003996DIL1 CSB-MP003996DIL1 CSB-EP003996DIL1-B |
Recombinant Danio rerio C5a anaphylatoxin chemotactic receptor (c5ar1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF003996DIL | Recombinant Danio rerio C5a anaphylatoxin chemotactic receptor (c5ar1) | in vitro E.coli expression system |
C5AR1 Proteins for Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP747619OEI1 CSB-EP747619OEI1 CSB-BP747619OEI1 CSB-MP747619OEI1 CSB-EP747619OEI1-B |
Recombinant Oncorhynchus mykiss C5a anaphylatoxin chemotactic receptor (c5ar1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF747619OEI | Recombinant Oncorhynchus mykiss C5a anaphylatoxin chemotactic receptor (c5ar1) | in vitro E.coli expression system |
C5AR1 Proteins for Oryctolagus cuniculus (Rabbit)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP874687RB1 CSB-EP874687RB1 CSB-BP874687RB1 CSB-MP874687RB1 CSB-EP874687RB1-B |
Recombinant Rabbit C5a anaphylatoxin chemotactic receptor (C5AR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF874687RB | Recombinant Rabbit C5a anaphylatoxin chemotactic receptor (C5AR1) | in vitro E.coli expression system |
