CALCRL
CALCR,即降钙素受体,别名Clr、Ct-r。它位于人类第19号染色体上,编码的蛋白质主要分布在内质网中,也存在于细胞核和细胞膜。CALCR的作用机制是通过与降钙素结合,激活G蛋白偶联受体信号通路,从而调节血钙水平,抑制骨吸收,并增加肾脏对钙的排泄。此外,CALCR在大脑中的表达表明它可能在中枢神经系统中也有特定功能,如增强垂体前叶激素的分泌、抑制食欲和胃酸分泌,以及可能与痛觉调节或自闭症的发病机制有关。CALCR在骨骼健康和骨疾病中扮演着重要角色,其基因突变与骨质疏松症有关,且在多种肿瘤中存在表达量的异常。
热销产品
CALCRL Antibody (CSB-PA788799)
验证数据

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA788799(CALCRL Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA788799(CALCRL Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)

Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human lung cancer tissue, Primary antibody: CSB-PA788799(CALCRL Antibody) at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds
CALCRL Antibodies
CALCRL for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA788799 | CALCRL Antibody | Human | ELISA,WB,IHC |
CSB-PA079870 | CALCRL Antibody | Human | ELISA,WB |
CALCRL Proteins
CALCRL Proteins for Bos taurus (Bovine)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP004440BO1 CSB-EP004440BO1 CSB-BP004440BO1 CSB-MP004440BO1 CSB-EP004440BO1-B |
Recombinant Bovine Calcitonin gene-related peptide type 1 receptor (CALCRL), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF004440BO | Recombinant Bovine Calcitonin gene-related peptide type 1 receptor (CALCRL) | in vitro E.coli expression system |
CALCRL Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP608100XBF1 CSB-EP608100XBF1 CSB-BP608100XBF1 CSB-MP608100XBF1 CSB-EP608100XBF1-B |
Recombinant Xenopus tropicalis Calcitonin gene-related peptide type 1 receptor (calcrl), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF608100XBF | Recombinant Xenopus tropicalis Calcitonin gene-related peptide type 1 receptor (calcrl) | in vitro E.coli expression system |
CALCRL Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP614981HU1 CSB-EP614981HU1 CSB-BP614981HU1 CSB-MP614981HU1 CSB-EP614981HU1-B |
Recombinant Human Calcitonin gene-related peptide type 1 receptor (CALCRL), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF614981HU | Recombinant Human Calcitonin gene-related peptide type 1 receptor (CALCRL) | in vitro E.coli expression system |
CALCRL Proteins for Rattus norvegicus (Rat)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP730880RA1 CSB-EP730880RA1 CSB-BP730880RA1 CSB-MP730880RA1 CSB-EP730880RA1-B |
Recombinant Rat Calcitonin gene-related peptide type 1 receptor (Calcrl), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF730880RA | Recombinant Rat Calcitonin gene-related peptide type 1 receptor (Calcrl) | in vitro E.coli expression system |
CALCRL Proteins for Xenopus laevis (African clawed frog)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP767255XBE1 CSB-EP767255XBE1 CSB-BP767255XBE1 CSB-MP767255XBE1 CSB-EP767255XBE1-B |
Recombinant Xenopus laevis Calcitonin gene-related peptide type 1 receptor (calcrl), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF767255XBE | Recombinant Xenopus laevis Calcitonin gene-related peptide type 1 receptor (calcrl) | in vitro E.coli expression system |
CALCRL Proteins for Oncorhynchus gorbuscha (Pink salmon) (Salmo gorbuscha)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP805844OBF1 CSB-EP805844OBF1 CSB-BP805844OBF1 CSB-MP805844OBF1 CSB-EP805844OBF1-B |
Recombinant Oncorhynchus gorbuscha Calcitonin gene-related peptide type 1 receptor (calcrl), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF805844OBF | Recombinant Oncorhynchus gorbuscha Calcitonin gene-related peptide type 1 receptor (calcrl) | in vitro E.coli expression system |
CALCRL Proteins for Sus scrofa (Pig)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP848799PI1 CSB-EP848799PI1 CSB-BP848799PI1 CSB-MP848799PI1 CSB-EP848799PI1-B |
Recombinant Pig Calcitonin gene-related peptide type 1 receptor (CALCRL), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF848799PI | Recombinant Pig Calcitonin gene-related peptide type 1 receptor (CALCRL) | in vitro E.coli expression system |
CALCRL Proteins for Mus musculus (Mouse)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP865649MO1 CSB-EP865649MO1 CSB-BP865649MO1 CSB-MP865649MO1 CSB-EP865649MO1-B |
Recombinant Mouse Calcitonin gene-related peptide type 1 receptor (Calcrl), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF865649MO | Recombinant Mouse Calcitonin gene-related peptide type 1 receptor (Calcrl) | in vitro E.coli expression system |
CALCRL Proteins for Paralichthys olivaceus (Japanese flounder) (Hippoglossus olivaceus)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP872788ERT1 CSB-EP872788ERT1 CSB-BP872788ERT1 CSB-MP872788ERT1 CSB-EP872788ERT1-B |
Recombinant Paralichthys olivaceus Calcitonin gene-related peptide type 1 receptor (calcrl), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF872788ERT | Recombinant Paralichthys olivaceus Calcitonin gene-related peptide type 1 receptor (calcrl) | in vitro E.coli expression system |