CARD14
CARD14，即胱冬酶吸引域家族成员14，别名PRP、PSORS2等，是MAGUK家族的一员。它源自人类基因，通过激活NF-κB信号通路，在免疫和炎症反应中发挥核心作用。CARD14尤其在皮肤细胞中表达丰富，对维护皮肤屏障及防御外界病原体至关重要。其异常激活与牛皮癣等皮肤疾病的发病紧密相关，可能通过促进角质细胞增生和炎症反应导致疾病发生。因此，CARD14不仅是理解皮肤生物学和免疫调节机制的关键，也是开发针对皮肤疾病新疗法的潜在靶点。
热销产品
CARD14 Antibody (CSB-PA883622LA01HU)
验证数据
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA883622LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA883622LA01HU at dilution of 1:100
Immunofluorescence staining of Hela cells with CSB-PA883622LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
CARD14 Antibodies
CARD14 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA004517GA01HU | CARD14 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA060134 | CARD14 Antibody | Human,Mouse | IHC, IF, ELISA |
| CSB-PA592611 | CARD14 Antibody | Human | ELISA,WB,IHC |
| CSB-PA448323 | CARD14 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA883622LA01HU | CARD14 Antibody | Human | ELISA, IHC, IF |
CARD14 Proteins
CARD14 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP860374MO CSB-EP860374MO CSB-BP860374MO CSB-MP860374MO CSB-EP860374MO-B |
Recombinant Mouse Caspase recruitment domain-containing protein 14 (Card14) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CARD14 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP883622HU CSB-EP883622HU CSB-BP883622HU CSB-MP883622HU CSB-EP883622HU-B |
Recombinant Human Caspase recruitment domain-containing protein 14 (CARD14), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
