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CCL17

CCL17,即C-C基序趋化因子配体17,别名A152E53、ABCD2、C-C motif chemokine 17。它是一种小分子肽,属于CC型趋化因子,主要通过与其膜受体CCR4结合发挥生物学功能。CCL17在多种T淋巴细胞亚群的细胞膜表面表达,尤其在辅助性T细胞上表达较高。它具有多样的生物学功能,参与炎症、超敏反应、自身免疫性疾病以及肿瘤微环境的调节。研究发现CCL17可能通过调节性T细胞(Treg)促进肿瘤生长与转移,但在特定条件下也可能具有抗肿瘤免疫作用。此外,CCL17在心血管老化中的作用也受到关注,其抑制可能成为治疗心血管老化的潜在策略。

热销产品

CCL17 Antibody (CSB-PA856406LA01HU)

验证数据

CSB-PA856406LA01HU

Immunohistochemistry of paraffin-embedded human glioma using CSB-PA856406LA01HU at dilution of 1:100

CSB-PA856406LA01HU

Immunohistochemistry of paraffin-embedded human cervical cancer using CSB-PA856406LA01HU at dilution of 1:100

CCL17 Antibodies

CCL17 for Homo sapiens (Human)

CCL17 Proteins

CCL17 Proteins for Macaca mulatta (Rhesus macaque)

CCL17 Proteins for Felis catus (Cat) (Felis silvestris catus)

CCL17 Proteins for Homo sapiens (Human)

CCL17 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

CCL17 ELISA Kit

CCL17 ELISA Kit for Homo sapiens (Human)

CCL17 ELISA Kit for Monkey

CCL17 ELISA Kit for Canis lupus familiaris (Dog) (Canis familiaris)