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CCL21

CCL21,即C-C基序趋化因子配体21,别名ECL、SLC、CKb9、TCA4、SCYA21。CCL21是一种小分子细胞因子,属于CC亚家族的趋化因子,主要在淋巴管起始处和淋巴器官中组成型表达,存在于几种基质细胞和高内皮小静脉(HEV)上,可以与糖胺聚糖(GAG)结合并固定在内皮细胞表面。CCL21通过与趋化因子受体CCR7和CXCR3结合,发挥其生物学功能。CCL21对胸腺细胞和活化的T细胞具有体外趋化作用,但对B细胞、巨噬细胞或中性粒细胞没有趋化作用。CCL21也是一种有效的T细胞迁移和粘附刺激物,可以促进T细胞向次级淋巴器官的迁移,对淋巴细胞归巢至二级淋巴器官中发挥作用,具有重要的免疫调节作用。

热销产品

Recombinant Human C-C motif chemokine 21 (CCL21) (CSB-EP004785HUc0)

验证数据

CSB-EP004785HUc0

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CCL21 Antibody (CSB-PA576836)

验证数据

CSB-PA576836

The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA576836(CCL21 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)

CSB-PA576836

The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA576836(CCL21 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)

CCL21 Antibodies

CCL21 for Homo sapiens (Human)

CCL21 Proteins

CCL21 Proteins for Homo sapiens (Human)

CCL21 Proteins for Macaca mulatta (Rhesus macaque)

CCL21 ELISA Kit

CCL21 ELISA Kit for Homo sapiens (Human)