CCR1
CCR1，即趋化因子受体1，别名CCL3受体、CD191。CCR1是一种G蛋白偶联受体（GPCR），主要表达在髓系细胞如单核细胞、巨噬细胞以及某些T细胞和B细胞上。CCR1的作用机制涉及其与配体结合后，激活G蛋白介导的信号通路，包括磷脂酶C（PLC）和腺苷酸环化酶（AC）等，导致细胞内钙离子水平变化、肌醇三磷酸（IP3）产生和cAMP水平变化，进而引发细胞的趋化运动和功能变化。CCR1在免疫应答和炎症反应中发挥关键作用。它参与免疫细胞的招募到炎症部位，促进病原体清除和组织修复。CCR1的功能异常与多种疾病的发生发展有关，包括哮喘、动脉粥样硬化、多发性硬化和某些肿瘤。CCR1及其配体的相互作用在疾病的发病机制中起着重要作用，并成为潜在的治疗靶点。
热销产品
Recombinant Human C-C chemokine receptor type 1 (CCR1) (CSB-CF004839HU)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
CCR1 Antibody (CSB-PA004839LA01HU)
验证数据
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA004839LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA004839LA01HU at dilution of 1:100
Immunofluorescent analysis of U251 cells using CSB-PA004839LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
CCR1 Antibodies
CCR1 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA004839LA01HU | CCR1 Antibody | Human | ELISA, IHC, IF |
CCR1 Proteins
CCR1 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP004839HU1 CSB-BP004839HU1 CSB-MP004839HU1 CSB-EP004839HU1-B |
Recombinant Human C-C chemokine receptor type 1 (CCR1), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004839HU | Recombinant Human C-C chemokine receptor type 1 (CCR1) | in vitro E.coli expression system |
| CSB-EP004839HU1 | Recombinant Human C-C chemokine receptor type 1 (CCR1), partial | E.coli |
CCR1 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP004839MO1 CSB-EP004839MO1 CSB-BP004839MO1 CSB-MP004839MO1 CSB-EP004839MO1-B |
Recombinant Mouse C-C chemokine receptor type 1 (Ccr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004839MO | Recombinant Mouse C-C chemokine receptor type 1 (Ccr1) | in vitro E.coli expression system |
CCR1 Proteins for Macaca mulatta (Rhesus macaque)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP004839MOW1 CSB-EP004839MOW1 CSB-BP004839MOW1 CSB-MP004839MOW1 CSB-EP004839MOW1-B |
Recombinant Macaca mulatta (Rhesus macaque) C-C chemokine receptor type 1 (CCR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004839MOW | Recombinant Macaca mulatta (Rhesus macaque) C-C chemokine receptor type 1 (CCR1) | in vitro E.coli expression system |
CCR1 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP018378SXV1 CSB-EP018378SXV1 CSB-BP018378SXV1 CSB-MP018378SXV1 CSB-EP018378SXV1-B |
Recombinant Schizosaccharomyces pombe NADPH--cytochrome P450 reductase (ccr1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF018378SXV | Recombinant Schizosaccharomyces pombe NADPH--cytochrome P450 reductase (ccr1) | in vitro E.coli expression system |
CCR1 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP650508MOV CSB-EP650508MOV CSB-BP650508MOV CSB-MP650508MOV CSB-EP650508MOV-B |
Recombinant Macaca fascicularis C-C chemokine receptor type 1 (CCR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CCR1 Proteins for Arabidopsis thaliana (Mouse-ear cress)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP879677DOA CSB-EP879677DOA CSB-BP879677DOA CSB-MP879677DOA CSB-EP879677DOA-B |
Recombinant Arabidopsis thaliana Serine/threonine-protein kinase-like protein CCR1 (CCR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
