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CD2

CD2,即T细胞分化抗原2,别名Tp44、LFA-2、OKT11、T2等。它是一种由CD2基因编码的细胞表面糖蛋白,属于免疫球蛋白超家族成员,主要表达在所有成熟T细胞和一些自然杀伤(NK)细胞表面。CD2的作用机制涉及与细胞外配体如CD58结合,参与T细胞的激活、增殖和免疫突触的形成,调节T细胞与其他免疫细胞的相互作用。CD2的功能异常与某些自身免疫性疾病和免疫缺陷有关,例如,CD2基因的突变可能导致某些类型的免疫缺陷。因此,CD2是免疫学研究和相关疾病治疗中的一个潜在靶点。

热销产品

Recombinant Human T-cell surface antigen CD2 (CD2), partial (CSB-EP004894HU)

验证数据

CSB-EP004894HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CD2 Antibody (CSB-PA004894LA01HU)

验证数据

CSB-PA004894LA01HU

Immunofluorescence staining of Hela cells with CSB-PA004894LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

CSB-PA004894LA01HU

Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA004894LA01HU at dilution of 1:100

CSB-PA004894LA01HU

Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA004894LA01HU at dilution of 1:100

CD2 Antibodies

CD2 for Homo sapiens (Human)

CD2 for H, M, R

CD2 Proteins

CD2 Proteins for Equus caballus (Horse)

CD2 Proteins for Rattus norvegicus (Rat)

CD2 Proteins for Homo sapiens (Human)

CD2 Proteins for Mus musculus (Mouse)

CD2 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)