CHRM1
CHRM1，即胆碱能受体毒蕈碱1，别名包括毒蕈碱M1受体、乙酰胆碱受体毒蕈碱1。它是一种G蛋白偶联受体，由CHRM1基因编码，在中枢神经系统、视网膜和泌尿系统中表达。CHRM1的作用机制主要是通过与乙酰胆碱结合，激活G蛋白，进而抑制腺苷酸环化酶活性、促进磷酸肌醇的降解和调节钾通道，从而介导多种细胞反应。CHRM1在生物学上的意义非常广泛，它参与调节迷走神经诱导的支气管收缩、胃肠道的酸分泌以及认知功能等。此外，CHRM1的功能异常与多种疾病有关，包括Lambert-Eaton肌无力综合征、哮喘、重症肌无力、焦虑症、心传导阻滞、帕瑞特腺癌、阿尔茨海默病、精神分裂症等。
热销产品
Recombinant Human Muscarinic acetylcholine receptor M1 (CHRM1), partial (CSB-EP005381HU1)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
验证数据
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA576885(CHRM1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA576885(CHRM1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
CHRM1 Antibodies
CHRM1 for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA005381HA01RA | Chrm1 Antibody | Rat | ELISA, WB |
CHRM1 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA006806 | CHRM1 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA759611 | CHRM1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA576885 | CHRM1 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA005381PA01HU | CHRM1 Antibody | Human | ELISA, IF |
| CSB-PA005381PD01HU | CHRM1 Antibody, Biotin conjugated | Human | ELISA |
CHRM1 Proteins
CHRM1 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP005381HU1 CSB-BP005381HU1 CSB-MP005381HU1 CSB-EP005381HU1-B |
Recombinant Human Muscarinic acetylcholine receptor M1 (CHRM1), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF005381HU | Recombinant Human Muscarinic acetylcholine receptor M1 (CHRM1) | in vitro E.coli expression system |
| CSB-EP005381HU1 | Recombinant Human Muscarinic acetylcholine receptor M1 (CHRM1), partial | E.coli |
CHRM1 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP005381MO1 CSB-EP005381MO1 CSB-BP005381MO1 CSB-MP005381MO1 CSB-EP005381MO1-B |
Recombinant Mouse Muscarinic acetylcholine receptor M1 (Chrm1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF005381MO | Recombinant Mouse Muscarinic acetylcholine receptor M1 (Chrm1) | in vitro E.coli expression system |
CHRM1 Proteins for Macaca mulatta (Rhesus macaque)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP005381MOW1 CSB-EP005381MOW1 CSB-BP005381MOW1 CSB-MP005381MOW1 CSB-EP005381MOW1-B |
Recombinant Macaca mulatta (Rhesus macaque) Muscarinic acetylcholine receptor M1 (CHRM1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF005381MOW | Recombinant Macaca mulatta (Rhesus macaque) Muscarinic acetylcholine receptor M1 (CHRM1) | in vitro E.coli expression system |
CHRM1 Proteins for Sus scrofa (Pig)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP005381PI1 CSB-EP005381PI1 CSB-BP005381PI1 CSB-MP005381PI1 CSB-EP005381PI1-B |
Recombinant Pig Muscarinic acetylcholine receptor M1 (CHRM1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF005381PI | Recombinant Pig Muscarinic acetylcholine receptor M1 (CHRM1) | in vitro E.coli expression system |
CHRM1 Proteins for Pongo abelii (Sumatran orangutan)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP712902PYX1 CSB-EP712902PYX1 CSB-BP712902PYX1 CSB-MP712902PYX1 CSB-EP712902PYX1-B |
Recombinant Pongo abelii Muscarinic acetylcholine receptor M1 (CHRM1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF712902PYX | Recombinant Pongo abelii Muscarinic acetylcholine receptor M1 (CHRM1) | in vitro E.coli expression system |
CHRM1 Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP005381RA | Recombinant Rat Muscarinic acetylcholine receptor M1 (Chrm1), partial | Yeast |
| CSB-EP005381RA | Recombinant Rat Muscarinic acetylcholine receptor M1 (Chrm1), partial | E.coli |
| CSB-BP005381RA CSB-MP005381RA CSB-EP005381RA-B |
Recombinant Rat Muscarinic acetylcholine receptor M1 (Chrm1), partial | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CHRM1 ELISA Kit
CHRM1 ELISA Kit for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-EL005381RA | Rat Muscarinic acetylcholine receptor M1(CHRM1) ELISA kit | serum, plasma, tissue homogenates, cell lysates. | 0.27 ng/ml |
