COL4A3
COL4A3，即胶原蛋白IV型α3链，别名Collagen type IV alpha 3 chain，属于胶原蛋白家族，是IV型胶原蛋白的一个亚型。COL4A3基因位于人染色体2q36-q37上，含有52个外显子，编码产物为8,114 bp的mRNA和162,000的蛋白质。
COL4A3的分布仅限于具有组织特异性的基底膜，如肾小球基底膜、耳蜗基底膜、前晶状体囊的眼基底膜、Descemet膜、卵巢和睾丸基底膜，以及肺泡毛细血管基底膜。COL4A3在细胞黏附功能中起作用，参与多种肿瘤的侵袭和转移，包括乳腺癌、胃癌、肺癌等。在肾脏疾病中，COL4A3基因的突变与Alport综合征相关，表现为遗传性肾病和听力损失。COL4A3还与良性家族性血尿、终末期肾病等疾病相关。
热销产品
Recombinant Human Collagen alpha-3 (IV) chain (COL4A3), partial (CSB-EP005743HU)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
COL4A3 Antibody (CSB-PA005743LA01HU)
验证数据
Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA005743LA01HU at dilution of 1:100
Human Collagen alpha-3(IV) chain (COL4A3) ELISA kit (CSB-EL005743HU)
验证数据
货号：CSB-EL005743HU
规格：96T/48T
灵敏度：0.039 ng/mL
检测范围：0.156 ng/mL-10 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
COL4A3 Antibodies
COL4A3 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA005743LA01HU | COL4A3 Antibody | Human | ELISA, IHC |
| CSB-PA005743LD01HU | COL4A3 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA000042 | Cleaved-COL4A3 (L1425) Antibody | Human | WB, ELISA |
| CSB-PA000064 | Cleaved-COL4A3 (P1426) Antibody | Human,Monkey | WB, ELISA |
| CSB-PA007069 | COL4A3 Antibody | Human | IHC, IF, ELISA |
| CSB-PA129196 | COL4A3 Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA345280 | COL4A3 Antibody | Human,Mouse | ELISA,IHC |
COL4A3 Proteins
COL4A3 Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP631697BO1 CSB-BP631697BO1 CSB-MP631697BO1 CSB-EP631697BO1-B |
Recombinant Bovine Collagen alpha-3 (IV) chain (COL4A3), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP631697BO1 | Recombinant Bovine Collagen alpha-3 (IV) chain (COL4A3), partial | E.coli |
COL4A3 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP865615MO CSB-BP865615MO CSB-MP865615MO CSB-EP865615MO-B |
Recombinant Mouse Collagen alpha-3 (IV) chain (Col4a3), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
COL4A3 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-EP005743HU | Recombinant Human Collagen alpha-3 (IV) chain (COL4A3), partial | E.coli |
COL4A3 ELISA Kit
COL4A3 ELISA Kit for Homo sapiens (Human)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-EL005743HU | Human Collagen alpha-3(IV) chain (COL4A3) ELISA kit | serum, plasma, tissue homogenates | 0.039 ng/mL |
