CTSK
CTSK，即组织蛋白酶K。别名Cathepsin K，它是一种由破骨细胞分泌的半胱氨酸蛋白酶，对骨吸收过程中的基质胶原的降解至关重要。CTSK主要在破骨细胞中表达，但在其他类型的细胞中也有发现，如软骨细胞和某些肿瘤细胞。CTSK在降解骨基质中起关键作用，其活性受多种因素调节，包括pH值和特异性抑制剂。CTSK的作用机制涉及其对骨基质中胶原蛋白的降解，这一过程对骨重塑和矿化至关重要。CTSK的异常表达或活性与多种疾病相关，包括但不限于骨疾病和肿瘤。在癌症中，CTSK可能参与肿瘤的生长和转移，其表达水平的变化与肿瘤的侵袭性和预后相关。CTSK被认为是治疗骨质疏松症和某些癌症的潜在靶点。
热销产品
Recombinant Human Cathepsin K (CTSK) (CSB-EP006192HU)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
CTSK Antibody (CSB-PA006192ESR1HU)
验证数据
Western blot
All lanes: CTSK antibody at 8μg/ml
Lane 1: MCF-7 whole cell lysate
Lane 2: Rat brain tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 37 kDa
Observed band size: 37 kDa
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA006192ESR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA006192ESR1HU at dilution of 1:100
Human Cathepsin K,cath-K ELISA Kit (CSB-E09438h)
验证数据
货号：CSB-E09438h
规格：96T/48T
灵敏度：1.95 pg/mL
检测范围：7.8 pg/mL-500 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
CTSK Antibodies
CTSK for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA006192LA01RA | Ctsk Antibody | Rat | ELISA, IHC |
CTSK for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA006192GA01HU | CTSK Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA15119A0Rb | CTSK Antibody | Human | ELISA |
| CSB-PA006192ESR1HU | CTSK Antibody | Human, Rat | ELISA, WB, IHC |
| CSB-PA039740 | CTSK Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA145433 | CTSK Antibody | Human,Mouse,Rat | ELISA,IHC |
CTSK Proteins
CTSK Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP006192HU | Recombinant Human Cathepsin K (CTSK) | Yeast |
| CSB-EP006192HU | Recombinant Human Cathepsin K (CTSK) | E.coli |
| CSB-BP006192HU CSB-MP006192HU CSB-EP006192HU-B |
Recombinant Human Cathepsin K (CTSK) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CTSK Proteins for Oryctolagus cuniculus (Rabbit)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP006192RB CSB-BP006192RB CSB-MP006192RB CSB-EP006192RB-B |
Recombinant Rabbit Cathepsin K (CTSK) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP006192RB | Recombinant Rabbit Cathepsin K (Ctsk) | E.coli |
CTSK Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP006192MO CSB-BP006192MO CSB-MP006192MO CSB-EP006192MO-B |
Recombinant Mouse Cathepsin K (Ctsk) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP006192MO | Recombinant Mouse Cathepsin K (Ctsk) | E.coli |
CTSK Proteins for Macaca mulatta (Rhesus macaque)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP006192MOW CSB-EP006192MOW CSB-BP006192MOW CSB-MP006192MOW CSB-EP006192MOW-B |
Recombinant Macaca mulatta (Rhesus macaque) Cathepsin K (CTSK) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CTSK Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP006192RA CSB-BP006192RA CSB-MP006192RA CSB-EP006192RA-B |
Recombinant Rat Cathepsin K (Ctsk) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP006192RA | Recombinant Rat Cathepsin K (Ctsk) | E.coli |
CTSK Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP006192MOV CSB-BP006192MOV CSB-MP006192MOV CSB-EP006192MOV-B |
Recombinant Macaca fascicularis Cathepsin K (CTSK) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP006192MOV | Recombinant Macaca fascicularis Cathepsin K (CTSK) | E.coli |
CTSK Proteins for Gallus gallus (Chicken)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP006192CH CSB-EP006192CH CSB-BP006192CH CSB-MP006192CH CSB-EP006192CH-B |
Recombinant Chicken Cathepsin K (CTSK) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CTSK Proteins for Sus scrofa (Pig)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP006192PI CSB-EP006192PI CSB-BP006192PI CSB-MP006192PI CSB-EP006192PI-B |
Recombinant Pig Cathepsin K (CTSK) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CTSK Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP006192DO CSB-BP006192DO CSB-MP006192DO CSB-EP006192DO-B |
Recombinant Dog Cathepsin K (CTSK) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CTSK Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP006192BO CSB-EP006192BO CSB-BP006192BO CSB-MP006192BO CSB-EP006192BO-B |
Recombinant Bovine Cathepsin K (CTSK) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CTSK Proteins for Canis lupus familiaris (Dog) (Canis familiaris)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-EP006192DO | Recombinant Dog Cathepsin K (CTSK) | E.coli |
CTSK ELISA Kit
CTSK ELISA Kit for Homo sapiens (Human)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E09438h | Human Cathepsin K,cath-K ELISA Kit | serum, plasma, tissue homogenates | 1.95 pg/mL |
CTSK ELISA Kit for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E09440m | Mouse Cathepsin K,cath-K ELISA Kit | serum, plasma, tissue homogenates | 3.9 pg/mL |
CTSK ELISA Kit for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E09439r | Rat Cathepsin K,cath-K ELISA Kit | serum, plasma, tissue homogenates | 3.9 pg/mL |
