DDX5
DDX5，即DEAD盒解旋酶5，别名P68。它是一种依赖ATP的RNA解旋酶，属于DEAD盒解旋酶家族成员之一，主要分布在细胞核内。DDX5的作用机制涉及催化双链RNA解旋，参与基因转录的正负调节以及mRNA、rRNA和miRNA的合成、剪接和加工等过程。DDX5对多种转录因子具有激活作用，影响细胞增殖、分化、细胞骨架重塑和细胞凋亡等，同时在肿瘤细胞的发生、侵袭和迁移中发挥作用，是影响肿瘤相关信号通路的关键因子。此外，DDX5的功能缺失可通过影响microRNA 125b的表达水平，上调非经典PRC1复合物里的RYBP，进而影响体细胞重编程过程。
热销产品
Recombinant Human Probable ATP-dependent RNA helicase DDX5 (DDX5) (CSB-EP006630HU)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP006630HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) DDX5.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP006630HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) DDX5.
验证数据
Western Blot analysis of HepG2 cells using p68 RNA Helicase Polyclonal Antibody
DDX5 Antibodies
DDX5 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA006630GA01HU | DDX5 Antibody | Human,Mouse,Rat | ELISA |
| CSB-PA006630ESR2HU | DDX5 Antibody | Human | ELISA, WB, IHC |
| CSB-PA003685 | DDX5 Antibody | Human,Mouse,Rat | WB, IF, ELISA |
| CSB-PA007714 | Phospho-DDX5 (Y593) Antibody | Human,Mouse,Rat | IHC, IF, ELISA |
| CSB-RA231179A0HU | DDX5 Recombinant Monoclonal Antibody | Human, Mouse | ELISA, WB, IHC, IF, FC |
DDX5 Proteins
DDX5 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP006630HU CSB-BP006630HU CSB-MP006630HU CSB-EP006630HU-B |
Recombinant Human Probable ATP-dependent RNA helicase DDX5 (DDX5) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP006630HU | Recombinant Human Probable ATP-dependent RNA helicase DDX5 (DDX5) | E.coli |
