DIABLO
DIABLO，即细胞凋亡诱导因子SMAC模拟蛋白，别名DBOH、DFNA64、SMAC3，由DIABLO基因编码。它是一种位于线粒体间隙的蛋白质，在细胞应激反应中发挥作用。DIABLO的作用机制是通过模拟SMAC蛋白的功能，促进细胞凋亡，抑制IAPs（凋亡抑制蛋白）的活性，从而推动细胞程序性死亡。DIABLO在细胞对氧化应激、DNA损伤和其他形式的细胞压力的响应中具有重要作用。生物学意义上，DIABLO参与调控细胞生存与死亡的平衡，其异常表达与多种疾病有关，包括癌症、神经退行性疾病等，是细胞凋亡研究和相关疾病治疗中的潜在靶点。
热销产品
Recombinant Human Diablo homolog, mitochondrial (DIABLO) (CSB-EP865113HU)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
DIABLO Antibody (CSB-PA865113LA01HU)
验证数据
Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA865113LA01HU at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CSB-PA865113LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
DIABLO Antibodies
DIABLO for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA006888GA01HU | DIABLO Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA592293 | DIABLO Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA966330 | DIABLO Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA865113LA01HU | DIABLO Antibody | Human | ELISA, IHC, IF |
DIABLO Proteins
DIABLO Proteins for Xenopus laevis (African clawed frog)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP389935XBE CSB-EP389935XBE CSB-BP389935XBE CSB-MP389935XBE CSB-EP389935XBE-B |
Recombinant Xenopus laevis Diablo homolog, mitochondrial (diablo) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DIABLO Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP611189XBF CSB-EP611189XBF CSB-BP611189XBF CSB-MP611189XBF CSB-EP611189XBF-B |
Recombinant Xenopus tropicalis Diablo homolog, mitochondrial (diablo) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DIABLO Proteins for Pongo abelii (Sumatran orangutan)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP732738PYX CSB-EP732738PYX CSB-BP732738PYX CSB-MP732738PYX CSB-EP732738PYX-B |
Recombinant Pongo abelii Diablo homolog, mitochondrial (DIABLO) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DIABLO Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP865113HU CSB-BP865113HU CSB-MP865113HU CSB-EP865113HU-B |
Recombinant Human Diablo homolog, mitochondrial (DIABLO) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP865113HU | Recombinant Human Diablo homolog, mitochondrial (DIABLO) | E.coli |
DIABLO Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP878067MO CSB-EP878067MO CSB-BP878067MO CSB-MP878067MO CSB-EP878067MO-B |
Recombinant Mouse Diablo homolog, mitochondrial (Diablo) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
