DRD5
DRD5，即多巴胺受体D5，别名DRD1B、DRD1L2。这是一种G蛋白偶联受体（GPCR），主要在大脑边缘区域的神经元中表达，尤其在前额叶皮层和海马体中。DRD5的作用机制涉及与多巴胺的结合，激活G蛋白，进而影响细胞内信号传导，包括cAMP水平的变化和离子通道的调节。DRD5在调节认知功能、情绪和运动控制中起着重要作用。它与多巴胺系统的其他受体一起，参与调节奖赏、动机和注意力等过程。DRD5的异常表达或功能与多种神经精神疾病相关，包括精神分裂症、帕金森病和药物成瘾。此外，DRD5也是药物开发的重要靶点，其激动剂可能有助于治疗认知障碍和神经退行性疾病。研究还发现，多巴胺通过DRD5-ARRB2-PP2A信号轴抑制TRAF6介导的NF-κB炎症信号和系统性炎症反应，揭示了DRD5在神经免疫调节中的新机制。
热销产品
验证数据
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA568903(DRD5 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human ovarian cancer tissue, Primary antibody: CSB-PA568903(DRD5 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
DRD5 Antibodies
DRD5 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA007182GA01HU | DRD5 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA007182EA01HU | DRD5 Antibody | Human, Mouse | ELISA, WB, IHC, IF |
| CSB-PA007182EC01HU | DRD5 Antibody, FITC conjugated | Human | |
| CSB-PA568903 | DRD5 Antibody | Human | ELISA,WB,IHC |
DRD5 Proteins
DRD5 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP007182HU1 CSB-EP007182HU1 CSB-BP007182HU1 CSB-MP007182HU1 CSB-EP007182HU1-B |
Recombinant Human D (1B) dopamine receptor (DRD5), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF007182HU | Recombinant Human D (1B) dopamine receptor (DRD5) | in vitro E.coli expression system |
DRD5 Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP007182RA1 CSB-EP007182RA1 CSB-BP007182RA1 CSB-MP007182RA1 CSB-EP007182RA1-B |
Recombinant Rat D (1B) dopamine receptor (Drd5), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF007182RA | Recombinant Rat D (1B) dopamine receptor (Drd5) | in vitro E.coli expression system |
DRD5 Proteins for Xenopus laevis (African clawed frog)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP331478XBE1 CSB-EP331478XBE1 CSB-BP331478XBE1 CSB-MP331478XBE1 CSB-EP331478XBE1-B |
Recombinant Xenopus laevis D (1B) dopamine receptor, partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF331478XBE | Recombinant Xenopus laevis D (1B) dopamine receptor | in vitro E.coli expression system |
DRD5 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP804368MO1 CSB-EP804368MO1 CSB-BP804368MO1 CSB-MP804368MO1 CSB-EP804368MO1-B |
Recombinant Mouse D (1B) dopamine receptor (Drd5), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF804368MO | Recombinant Mouse D (1B) dopamine receptor (Drd5) | in vitro E.coli expression system |
DRD5 Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP850127BO CSB-EP850127BO CSB-BP850127BO CSB-MP850127BO CSB-EP850127BO-B |
Recombinant Bovine D (1B) dopamine receptor (DRD5), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DRD5 Proteins for Macaca mulatta (Rhesus macaque)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP853260MOW CSB-EP853260MOW CSB-BP853260MOW CSB-MP853260MOW CSB-EP853260MOW-B |
Recombinant Macaca mulatta D (1B) dopamine receptor (DRD5), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
