ENG

ENG全称为内皮联蛋白（Endoglin），别名CD105。它是一种I型跨膜糖蛋白，主要表达于内皮细胞、成纤维细胞和血管平滑肌细胞等。内皮联蛋白作为TGF-β家族的辅助受体，通过与TGF-β受体复合体相互作用，调节细胞的增殖、迁移和分化，从而在血管生成和稳态维持中发挥关键作用。内皮联蛋白还参与炎症反应和免疫应答的调节。
ENG基因突变可导致1型遗传性出血性毛细血管扩张症（HHT1），表现为血管发育不良和反复出血。在肿瘤中，内皮联蛋白高表达与肿瘤血管生成和转移密切相关，因此成为抗肿瘤治疗的重要靶点。针对内皮联蛋白的药物研发正在推进，旨在通过抑制其功能来阻断肿瘤血管生成。

热销产品

ENG Antibody (CSB-PA400072)

验证数据

Western blot analysis of K562 3T3 lysate, antibody was diluted at 500. Secondary antibody was diluted at 1:20000

Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:200

Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:200

ENG Antibody

ENG Protein

ENG ELISA Kit

ENG Antibodies

ENG for Homo sapiens (Human)

产品货号	产品名称	种属反应性	应用类型
CSB-PA007667GA01HU	ENG Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA400072	ENG Antibody	Human	WB, IHC, ELISA
CSB-PA007667LA01HU	ENG Antibody	Human	ELISA, IF
CSB-PA007667LC01HU	ENG Antibody, FITC conjugated	Human
CSB-PA007667LD01HU	ENG Antibody, Biotin conjugated	Human	ELISA
CSB-MA294403	ENG Monoclonal Antibody	Human	ELISA, IHC

ENG Proteins

ENG Proteins for Homo sapiens (Human)

产品货号	产品名称	来源
CSB-YP007667HU1 CSB-EP007667HU1 CSB-BP007667HU1 CSB-MP007667HU1 CSB-EP007667HU1-B	Recombinant Human Endoglin (ENG), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF007667HU	Recombinant Human Endoglin (ENG)	in vitro E.coli expression system

ENG Proteins for Sus scrofa (Pig)

产品货号	产品名称	来源
CSB-YP007667PI1 CSB-EP007667PI1 CSB-BP007667PI1 CSB-MP007667PI1 CSB-EP007667PI1-B	Recombinant Pig Endoglin (ENG), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF007667PI	Recombinant Pig Endoglin (ENG)	in vitro E.coli expression system

ENG Proteins for Mus musculus (Mouse)

产品货号	产品名称	来源
CSB-YP007667MO CSB-EP007667MO CSB-BP007667MO CSB-MP007667MO CSB-EP007667MO-B	Recombinant Mouse Endoglin (Eng), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli