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FAS

FAS,即肿瘤坏死因子受体超家族成员6,别名APO-1、CD95、TNFRSF6,是一种细胞表面死亡受体,属于肿瘤坏死因子受体超家族。FAS主要多种组织细胞表面表达,少量以可溶性形式存在于血浆中。
FAS通过与其配体FasL结合,形成死亡诱导信号复合物(DISC),进而激活下游的caspase凋亡级联反应,引起细胞凋亡。FAS在免疫系统中发挥重要作用,特别是在细胞凋亡、免疫耐受和抗肿瘤免疫应答中。FAS信号通路的异常活化或抑制与多种疾病相关,包括自身免疫性疾病、某些类型的癌症以及免疫缺陷疾病。

热销产品

Recombinant Human Fatty acid synthase (FASN), partial (CSB-EP008435HU)

验证数据

CSB-EP008435HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

FASN Recombinant Monoclonal Antibody (CSB-RA240595A0HU)

验证数据

CSB-RA240595A0HU

Immunofluorescence staining of Hela Cells with CSB-RA240595A0HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4℃. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).

CSB-RA240595A0HU

Overlay histogram showing A549 cells stained with CSB-RA240595A0HU (red line) at 1:50. The cells were fixed with 70% Ethylalcohol (18h) and then incubated in 10% normal goat serum to block non-specific protein-protein interactions followedby the antibody (1µg/1*106 cells) for 1 h at 4℃.The secondary antibody used was FITC-conjugated goat anti-rabbit IgG (H+L) at 1/200 dilution for 30min at 4℃. Control antibody (green line) was Rabbit IgG (1µg/1*106 cells) used under the same conditions. Acquisition of >10,000 events was performed.

Human Fatty acid synthase(FASN) ELISA kit (CSB-EL008435HU)

验证数据

CSB-EL008435HU 标准曲线

货号:CSB-EL008435HU

规格:96T/48T

灵敏度:0.39 ng/mL

检测范围:1.56 ng/mL-100 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

FAS Antibodies

FAS for Homo sapiens (Human)

FAS Proteins

FAS Proteins for Mus musculus (Mouse)

FAS Proteins for Homo sapiens (Human)

FAS Proteins for Bos taurus (Bovine)

FAS Proteins for Sus scrofa (Pig)

FAS Proteins for Rattus norvegicus (Rat)

FAS Proteins for Macaca nemestrina (Pig-tailed macaque)

FAS Proteins for Macaca mulatta (Rhesus macaque)

FAS Proteins for Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)

FAS Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

FAS ELISA Kit

FAS ELISA Kit for Homo sapiens (Human)

FAS ELISA Kit for Rattus norvegicus (Rat)

FAS ELISA Kit for Mus musculus (Mouse)