GSDME
GSDME，别名DFNA5、ICERE-1。它来源于人体细胞，是一种具有膜穿孔活性的蛋白质。GSDME在细胞中的作用机制主要是通过被Caspase 3切割激活，诱导细胞从凋亡向细胞焦亡转换。在生物学上，GSDME具有多重意义，包括参与神经退行性疾病的发生、调节炎症反应，以及作为癌症免疫疗法的潜在靶点。它的发现和研究为理解细胞死亡机制、治疗神经退行性疾病和癌症提供了新的视角和策略。
热销产品
Recombinant Human Gasdermin-E (GSDME) (CSB-EP006766HU)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
GSDME Antibody (CSB-PA006766LA01HU)
验证数据
Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA006766LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA006766LA01HU at dilution of 1:100
Immunofluorescent analysis of Hela cells using CSB-PA006766LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
GSDME Antibodies
GSDME for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA006766LA01HU | GSDME Antibody | Human | ELISA, IHC, IF |
| CSB-PA006766GA01HU | DFNA5 Antibody | Human,Mouse | ELISA,WB |
| CSB-PA006766ESR1HU | GSDME Antibody | Human | ELISA, WB, IHC |
| CSB-PA006766ESR2HU | GSDME Antibody | Human | ELISA, IHC |
| CSB-PA004659 | DFNA5 Antibody | Human,Rat | WB, ELISA |
GSDME Proteins
GSDME Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP006766HU CSB-BP006766HU CSB-MP006766HU CSB-EP006766HU-B |
Recombinant Human Gasdermin-E (GSDME) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP006766HU | Recombinant Human Gasdermin-E (GSDME) | E.coli |
