IL1RAP
IL1RAP，即白细胞介素1受体辅助蛋白，别名IL-1RAcP、C3orf13等，是IL-1信号通路的关键分子。它源自基因表达，通过与IL-1受体结合，增强IL-1信号传导，激活下游炎症通路，调节免疫细胞活性与炎症反应。IL1RAP在免疫调节、细胞增殖分化中扮演重要角色，其异常表达关联多种疾病，如癌症与自身免疫病。因此，IL1RAP成为疾病治疗的新靶点，针对其的疗法正逐步进入临床试验。
热销产品
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human IL1RAP at 2 μg/ml can bind Anti-IL1RAP recombinant antibody (CSB-RA878844MA1HU). The EC50 is 0.9667-1.477 ng/mL.
The purity of IL1RAP was greater than 95% as determined by SEC-HPLC
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis IL1RAP at 2 μg/ml can bind Anti-IL1RAP recombinant antibody (CSB-RA878844MA1HU). The EC50 is 0.9099-1.181 ng/mL.
The purity of IL1RAP was greater than 95% as determined by SEC-HPLC
IL1RAP Antibodies
IL1RAP for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA878844ESR1HU | IL1RAP Antibody | Human | ELISA, IHC |
| CSB-PA238165 | IL1RAP Antibody | Human,Mouse,Rat | ELISA,IHC |
IL1RAP Proteins
IL1RAP Proteins for Macaca mulatta (Rhesus macaque)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011623MOW1 CSB-EP011623MOW1 CSB-BP011623MOW1 CSB-MP011623MOW1 CSB-EP011623MOW1-B |
Recombinant Macaca mulatta (Rhesus macaque) Interleukin-1 receptor accessory protein (IL1RAP), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF011623MOW | Recombinant Macaca mulatta (Rhesus macaque) Interleukin-1 receptor accessory protein (IL1RAP) | in vitro E.coli expression system |
IL1RAP Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP730751MO CSB-EP730751MO CSB-BP730751MO CSB-MP730751MO CSB-EP730751MO-B |
Recombinant Mouse Interleukin-1 receptor accessory protein (Il1rap), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL1RAP Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP733954RA CSB-BP733954RA CSB-MP733954RA CSB-EP733954RA-B |
Recombinant Rat Interleukin-1 receptor accessory protein (Il1rap), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL1RAP Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP878844HU CSB-EP878844HU CSB-BP878844HU CSB-EP878844HU-B |
Recombinant Human Interleukin-1 receptor accessory protein (IL1RAP), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-MP878844HU | Recombinant Human Interleukin-1 receptor accessory protein (IL1RAP), partial (Active) | Mammalian cell |
