IL3
IL3，即白细胞介素3，别名Interleukin-3、MCGF。IL-3主要由活化的T细胞和NK细胞产生，此外，IL-1激活的人内皮细胞、IgE激活的小鼠肥大细胞和胎盘细胞等也能产生IL-3。IL-3的作用机制主要通过与其受体结合并触发细胞内信号传导过程来实现。IL-3与其受体α链（IL-3Rα）结合后，会进一步与β链（IL-3Rβ，CD131）结合，形成异源二聚体或寡聚体，从而激活受体相关的Janus激酶（JAK），主要是JAK2。激活的JAK2募集STAT5并介导其磷酸化，磷酸化的STAT5进入细胞核，诱导下游效应基因的转录。此外，IL-3还激活Ras-MAPK和磷酸肌醇3-激酶（PI3K）通路。IL-3是一种重要的造血生长因子，对多种细胞类型的发育起着关键作用，包括粒细胞、单核细胞、巨噬细胞、嗜酸性粒细胞、嗜碱性粒细胞和肥大细胞。IL-3还参与免疫调节、炎症反应以及血液系统疾病的治疗。
热销产品
Recombinant Human Interleukin-3 (IL3) (Active) (CSB-MP011652HU-WD)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
IL3 Antibody (CSB-PA011652ESR1HU)
验证数据
Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA011652ESR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA011652ESR1HU at dilution of 1:100
IL3 Antibodies
IL3 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA011652GA01HU | IL3 Antibody | Human | ELISA,WB |
| CSB-PA06725B0Rb | IL3 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA06725A0Rb | IL3 Antibody | Human | ELISA, IHC |
| CSB-PA011652ESR1HU | IL3 Antibody | Human | ELISA, IHC |
| CSB-PA196621 | IL3 Antibody | Human,Mouse | ELISA,WB |
IL3 Proteins
IL3 Proteins for Macaca mulatta (Rhesus macaque)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011652MOW CSB-EP011652MOW CSB-BP011652MOW CSB-MP011652MOW CSB-EP011652MOW-B |
Recombinant Macaca mulatta (Rhesus macaque) Interleukin-3 (IL3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP001981MOW | Recombinant Rhesus Macaque Interleukin-3 protein (IL3) | E.Coli |
IL3 Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011652BO CSB-BP011652BO CSB-MP011652BO CSB-EP011652BO-B |
Recombinant Bovine Interleukin-3 (IL3) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL3 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-EP011652MO CSB-BP011652MO CSB-MP011652MO CSB-EP011652MO-B |
Recombinant Mouse Interleukin-3 (Il3) | E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP003291MO | Recombinant Mouse Interleukin-3 protein (Il3), partial | E.Coli |
IL3 Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011652RA CSB-EP011652RA CSB-BP011652RA CSB-MP011652RA CSB-EP011652RA-B |
Recombinant Rat Interleukin-3 (Il3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL3 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011652HU CSB-BP011652HU CSB-EP011652HU-B |
Recombinant Human Interleukin-3 (IL3) | Yeast Baculovirus In Vivo Biotinylation in E.coli |
| CSB-EP011652HU | Recombinant Human Interleukin-3 (IL3) | E.coli |
| CSB-AP001701HU | Recombinant Human Interleukin-3 protein (IL3) | E.Coli |
| CSB-EP011652HUc7 | Recombinant Human Interleukin-3 (IL3) | E.coli |
| CSB-AP004521HU | Recombinant Human Interleukin-3 (IL3) (Active) | Mammalian cell |
| CSB-AP004531HU | Recombinant Human Interleukin-3 (IL3) (Active) | E.coli |
| CSB-AP005821HU | Recombinant Human Interleukin-3 (IL3), partial (Active) (GMP) | E.Coli |
| CSB-MP011652HU-WD | Recombinant Human Interleukin-3 (IL3) (Active) | Mammalian cell |
| CSB-YP011652HUd7 | Recombinant Human Interleukin-3 (IL3) (Active) | Yeast |
| CSB-MP011652HU | Recombinant Human Interleukin-3 (IL3) (Active) | Mammalian cell |
IL3 Proteins for Saguinus oedipus (Cotton-top tamarin)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011652SWB CSB-EP011652SWB CSB-BP011652SWB CSB-MP011652SWB CSB-EP011652SWB-B |
Recombinant Saguinus oedipus Interleukin-3 (IL3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL3 Proteins for Hylobates lar (Common gibbon)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP011652HXW CSB-EP011652HXW CSB-BP011652HXW CSB-MP011652HXW CSB-EP011652HXW-B |
Recombinant Hylobates lar Interleukin-3 (IL3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL3 Proteins for Callithrix jacchus (White-tufted-ear marmoset)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP632965CYL CSB-EP632965CYL CSB-BP632965CYL CSB-MP632965CYL CSB-EP632965CYL-B |
Recombinant Callithrix jacchus Interleukin-3 (IL3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL3 Proteins for Pan troglodytes (Chimpanzee)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP637919EQV CSB-EP637919EQV CSB-BP637919EQV CSB-MP637919EQV CSB-EP637919EQV-B |
Recombinant Pan troglodytes Interleukin-3 (IL3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL3 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP860200DO CSB-EP860200DO CSB-BP860200DO CSB-MP860200DO CSB-EP860200DO-B |
Recombinant Dog Interleukin-3 (IL3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL3 ELISA Kit
IL3 ELISA Kit for Homo sapiens (Human)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E04631h | Human Interleukin 3,IL-3 ELISA KIT | serum, plasma, tissue homogenates. | 15.6 pg/ml. |
IL3 ELISA Kit for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E04632m | Mouse Interleukin 3,IL-3 ELISA KIT | serum, plasma, tissue homogenates | 1.95 pg/mL |
IL3 ELISA Kit for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E07436r | Rat Interleukin 3,IL-3 ELISA KIT | serum, plasma, tissue homogenates | 0.78 pg/mL |
