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KISS1R

KISS1R,即吻素1受体,别名GPR54、KISS1R1。它是一种G蛋白偶联受体,由KISS1R基因编码,在下丘脑和垂体等部位表达。KISS1R的作用机制涉及与吻素1(KISS1)结合,激活Gq/11蛋白,进而促进磷脂酰肌醇4,5-二磷酸(PIP2)转化为肌醇三磷酸(IP3)和二酰甘油(DAG),调节细胞内钙离子浓度和蛋白激酶C(PKC)的活性。KISS1R在生物学上的意义主要体现在其对生殖系统、能量平衡和应激反应的调控作用。KISS1R的激活影响性激素的分泌和性行为,同时在调节食欲和身体组成方面发挥作用。此外,KISS1R的表达与神经内分泌疾病有关,是相关疾病研究和治疗的潜在靶点。

热销产品

KISS1R Antibody (CSB-PA248650)

验证数据

CSB-PA248650

The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA248650(KISS1R Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)

CSB-PA248650

The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA248650(KISS1R Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)

KISS1R Antibodies

KISS1R for Homo sapiens (Human)

KISS1R Proteins

KISS1R Proteins for Rattus norvegicus (Rat)

KISS1R Proteins for Mus musculus (Mouse)

KISS1R Proteins for Homo sapiens (Human)