KITLG
KITLG，即KIT配体，别名SCF、MGF、FPFH、DCUA等。它是一种由骨髓微环境中的基质细胞产生的酸性糖蛋白，由两个相同亚基非共价结合而成。KITLG的作用机制主要是通过与其受体c-Kit结合，激活下游的信号传导途径，如JAK/STAT、PI3K/AKT、ERK1/2和STAT3等，从而促进细胞增殖、分化和迁移。KITLG在胚胎期的生殖细胞和神经细胞发育、造血过程中发挥作用，成体中主要在造血过程中发挥作用。KITLG的异常表达与多种疾病相关，包括家族性进行性高色素沉着症、神经性耳聋、某些类型的癌症如鼻咽癌、膀胱癌和三阴性乳腺癌。KITLG在肿瘤微环境中的表达与肿瘤细胞的增殖、侵袭和转移密切相关，是癌症治疗中的潜在药物靶点。
热销产品
Recombinant Human Kit ligand (KITLG), partial (Active) (CSB-MP002061HU1)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
The ED50 as determined by the dose-dependent stimulation of the proliferation of MO7e cells is 1.813-3.203 ng/mL.
The purity of KITLG was greater than 95% as determined by SEC-HPLC
KITLG Antibodies
KITLG for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA012376ESR2HU | KITLG Antibody | Human | ELISA, WB |
| CSB-PA122514 | KITLG Antibody | Human | ELISA,WB |
KITLG Proteins
KITLG Proteins for Ovis aries (Sheep)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP012376SH1 CSB-EP012376SH1 CSB-BP012376SH1 CSB-MP012376SH1 CSB-EP012376SH1-B |
Recombinant Sheep Kit ligand (KITLG), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF012376SH | Recombinant Sheep Kit ligand (KITLG) | in vitro E.coli expression system |
KITLG Proteins for Felis catus (Cat) (Felis silvestris catus)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP012376CA1 CSB-EP012376CA1 CSB-BP012376CA1 CSB-MP012376CA1 CSB-EP012376CA1-B |
Recombinant Cat Kit ligand (KITLG), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF012376CA | Recombinant Cat Kit ligand (KITLG) | in vitro E.coli expression system |
KITLG Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP012376RA1 CSB-EP012376RA1 CSB-BP012376RA1 CSB-MP012376RA1 CSB-EP012376RA1-B |
Recombinant Rat Kit ligand (Kitlg), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF012376RA | Recombinant Rat Kit ligand (Kitlg) | in vitro E.coli expression system |
KITLG Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP012376MO1 CSB-EP012376MO1 CSB-BP012376MO1 CSB-EP012376MO1-B |
Recombinant Mouse Kit ligand (Kitlg), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-AP003151MO | Recombinant Mouse Kit ligand protein (Kitlg), partial (Active) | E.Coli |
| CSB-CF012376MO | Recombinant Mouse Kit ligand (Kitlg) | in vitro E.coli expression system |
| CSB-AP004071MO | Recombinant Mouse Kit ligand (Kitlg), partial (Active) | E.coli |
KITLG Proteins for Mustela vison (American mink) (Neovison vison)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP012376MVE CSB-EP012376MVE CSB-BP012376MVE CSB-MP012376MVE CSB-EP012376MVE-B |
Recombinant Mustela vison Kit ligand (KITLG), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KITLG Proteins for Coturnix coturnix japonica (Japanese quail) (Coturnix japonica)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP012376DXJ CSB-EP012376DXJ CSB-BP012376DXJ CSB-MP012376DXJ CSB-EP012376DXJ-B |
Recombinant Coturnix coturnix japonica Kit ligand (KITLG), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KITLG Proteins for Capra hircus (Goat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP012376GO CSB-EP012376GO CSB-BP012376GO CSB-MP012376GO CSB-EP012376GO-B |
Recombinant Goat Kit ligand (KITLG), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KITLG Proteins for Equus caballus (Horse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP012376HO CSB-EP012376HO CSB-BP012376HO CSB-MP012376HO CSB-EP012376HO-B |
Recombinant Horse Kit ligand (KITLG), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KITLG Proteins for Gallus gallus (Chicken)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP012376CH CSB-EP012376CH CSB-BP012376CH CSB-MP012376CH CSB-EP012376CH-B |
Recombinant Chicken Kit ligand (KITLG), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KITLG Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP012376BO CSB-BP012376BO CSB-MP012376BO CSB-EP012376BO-B |
Recombinant Bovine Kit ligand (KITLG), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KITLG Proteins for Sus scrofa (Pig)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP012376PI CSB-EP012376PI CSB-BP012376PI CSB-MP012376PI CSB-EP012376PI-B |
Recombinant Pig Kit ligand (KITLG), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KITLG Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-EP012376HU | Recombinant Human Kit ligand (KITLG), partial | E.coli |
| CSB-AP002061HU | Recombinant Human Kit ligand protein (KITLG), partial (Active) | E.Coli |
| CSB-CF012376HU(A4) | Recombinant Human Kit ligand (KITLG) | in vitro E.coli expression system |
| CSB-AP003741HU | Recombinant Human Kit ligand (KITLG), partial (Active) | E.coli |
| CSB-AP003881HU | Recombinant Human Kit ligand (KITLG), partial (Active) | Mammalian cell |
| CSB-MP002061HU1h6 | Recombinant Human Kit ligand (KITLG), partial | Mammalian cell |
| CSB-MP002061HU1 | Recombinant Human Kit ligand (KITLG), partial (Active) | Mammalian cell |
| CSB-MP002061HU-WD | Recombinant Human Kit ligand (KITLG)，Partial (Active) | Mammalian cell |
KITLG ELISA Kit
KITLG ELISA Kit for Homo sapiens (Human)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E04718h | Human Stem cell factor/mast cell growth factor,SCF/MGF ELISA kit | serum, plasma, cell culture supernates | 0.11 ng/mL |
KITLG ELISA Kit for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E04719m | Mouse Stem cell factor/mast cell growth factor,SCF/MGF ELISA kit | serum, plasma, tissue homogenates | 0.78 pg/mL |
KITLG ELISA Kit for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E04720r | Rat Stem cell factor/mast cell growth factor,SCF/MGF ELISA kit | serum, plasma, tissue homogenates | 1.56 pg/mL |
