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KLF4

KLF4。即Krüppel样因子4,别名GKLF、epithelial zinc finger protein EZF等。它是一种转录因子,主要在结肠癌、胃癌等多种癌症的肿瘤组织中表达,并在细胞增殖、分化、胚胎发育等重要生命过程中发挥作用。KLF4的作用机制涉及通过与下游基因启动子区的结合元件相结合,直接调控下游基因的转录。KLF4具有抑癌和促癌的双重调节作用,在肿瘤发生、血管重构等生理病理过程中起到重要作用。此外,KLF4是体细胞重编程为诱导多能干细胞(iPS细胞)的重要诱导因子之一,对于临床医学上基因治疗技术的应用具有潜在的研究价值。

热销产品

KLF4 Antibody (CSB-PA012394DSR2HU)

验证数据

CSB-PA012394DSR2HU

Western blot
All lanes: Krueppel-like factor 4 antibody at 5μg/ml + 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 55, 52, 46, 13, 7 kDa
Observed band size: 55 kDa

CSB-PA012394DSR2HU

Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA012394DSR2HU at dilution of 1:100

CSB-PA012394DSR2HU

Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA012394DSR2HU at dilution of 1:100

Human Krueppel-like factor 4(KLF4) ELISA kit (CSB-EL012394HU)

验证数据

CSB-EL012394HU 标准曲线

货号:CSB-EL012394HU

规格:96T/48T

灵敏度:4.6 pg/mL

检测范围:18.75 pg/mL-1200 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

KLF4 Antibodies

KLF4 for Homo sapiens (Human)

KLF4 Proteins

KLF4 Proteins for Homo sapiens (Human)

KLF4 Proteins for Mus musculus (Mouse)

KLF4 ELISA Kit

KLF4 ELISA Kit for Homo sapiens (Human)