MAGEA4
MAGEA4，即黑色素瘤相关抗原A4，别名MAGE-4、MAGE-41、MAGE-X2等。MAGEA4基因属于MAGE家族，位于人类的X号染色体上。MAGEA4的作用机制主要涉及其编码的蛋白质在细胞内的表达，这些蛋白质通常在肿瘤细胞中表达，而在正常组织中表达较低或不表达，尤其是在睾丸等免疫豁免部位。MAGEA4在肿瘤细胞中的表达可能与抑制细胞凋亡和促进肿瘤生长有关。此外，MAGEA4还可以作为免疫治疗的靶点，通过激活针对MAGEA4的免疫反应来攻击肿瘤细胞。MAGEA4在多种肿瘤中表达，包括肺癌、卵巢癌、黑色素瘤等，其表达水平与肿瘤的侵袭性和预后密切相关，MAGEA4的检测和靶向治疗具有重要的生物学意义。
热销产品
Recombinant Human Melanoma-associated antigen 4 (MAGEA4) (Active) (CSB-MP013330HU)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human MAGEA4 at 2 μg/ml can bind anti-MAGEA4 recombinant antibody, the EC50 is 30.33-43.10 ng/mL.
MAGEA4 Antibody (CSB-PA013330LA01HU)
验证数据
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA013330LA01HU at dilution of 1:100
MAGEA4 Antibodies
MAGEA4 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA013330GA01HU | MAGEA4 Antibody | Human | ELISA,IHC |
| CSB-PA059198 | MAGEA4 Antibody | Human | ELISA,IHC |
| CSB-PA179901 | MAGEA4 Antibody | Human | ELISA,IHC |
| CSB-PA013330LA01HU | MAGEA4 Antibody | Human | ELISA, IHC |
| CSB-PA013330LD01HU | MAGEA4 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA013330LC01HU | MAGEA4 Antibody, FITC conjugated | Human | |
| CSB-PA013330LB01HU | MAGEA4 Antibody, HRP conjugated | Human | ELISA |
| CSB-MA013330A0m | MAGEA4 Monoclonal Antibody | Human | ELISA, IHC, FC |
MAGEA4 Proteins
MAGEA4 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP013330HU CSB-EP013330HU CSB-BP013330HU CSB-EP013330HU-B |
Recombinant Human Melanoma-associated antigen 4 (MAGEA4) | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-EP013330HU(M) | Recombinant Human Melanoma-associated antigen 4 (MAGEA4) | E.coli |
| CSB-MP013330HU | Recombinant Human Melanoma-associated antigen 4 (MAGEA4) (Active) | Mammalian cell |
| CSB-EP013330HUb0 | Recombinant Human Melanoma-associated antigen 4 (MAGEA4) | E.coli |
