NFKB1
NFKB1，即核因子kappa B亚基1，别名p50，它是核因子-κB（NF-κB）/Rel蛋白家族的一员。NFKB1基因位于3号染色体上，编码的p50蛋白通常与p65（RelA）形成异二聚体，参与多种生物学过程，包括先天和适应性免疫、炎症、应激反应、B细胞发育和淋巴器官形成。在细胞质中，NF-κB与IκB蛋白结合并受到其抑制。当细胞受到炎症因子、脂多糖（LPS）、生长因子等刺激时，IKK复合体激活，导致IκB磷酸化和降解，释放NF-κB/Rel复合体。活性NF-κB/Rel复合体进一步激活，并转运入细胞核，诱导靶标基因表达。NFKB1在调节免疫反应和炎症过程中发挥关键作用，其异常激活与多种疾病的发生发展有关，包括自身免疫疾病、炎症性疾病和某些类型的癌症，是药物开发的重要靶点。
热销产品
Recombinant Human Nuclear factor NF-kappa-B p105 subunit (NFKB1) (CSB-EP015759HU)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Phospho-NFKB1 (Ser932) Antibody (CSB-PA142672)
验证数据
Western blot analysis of extracts from 293 cells untreated or treated with TNF-a using NFkB-p105(Phospho-Ser932) Antibody.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using NFkB-p105(Phospho-Ser932) Antibody(left) or the same antibody preincubated with blocking peptide(right).
Human Nuclear factor-kappa B,NF-κB ELISA Kit (CSB-E12107h)
验证数据
货号：CSB-E12107h
规格：96T/48T
灵敏度：0.078 ng/mL
检测范围：0.312 ng/mL-20 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
NFKB1 Antibodies
NFKB1 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA10354A0Rb | NFKB1 Antibody | Human | ELISA, WB, IHC, IF, ChIP |
| CSB-PA10354B0Rb | NFKB1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA10354C0Rb | NFKB1 Antibody, FITC conjugated | Human | |
| CSB-PA10354D0Rb | NFKB1 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA015759GA01HU | NFKB1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA142672 | Phospho-NFKB1 (Ser932) Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA283590 | Phospho-NFKB1 (Ser927) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA186775 | NFKB1 (Ab-337) Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA108426 | NFKB1 (Ab-893) Antibody | Human | ELISA,WB,IHC |
| CSB-PA696291 | NFKB1 (Ab-907) Antibody | Human | ELISA,WB,IHC |
| CSB-PA190132 | NFKB1 (Ab-932) Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA632717 | Phospho-NFKB1 (Ser337) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA258273 | Phospho-NFKB1 (Ser893) Antibody | Human | ELISA,IHC,IF |
| CSB-PA925652 | Phospho-NFKB1 (Ser907) Antibody | Human | ELISA,WB,IHC |
| CSB-PA000579 | Phospho-NFKB1 (S893) Antibody | Human | WB, IHC, ELISA |
| CSB-PA000580 | Phospho-NFKB1 (S907) Antibody | Human | WB, IHC, IP, ELISA |
| CSB-PA000581 | Phospho-NFKB1 (S932) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA000683 | Phospho-NFKB1 (S337) Antibody | Human,Mouse | WB, IHC, ELISA |
| CSB-PA000730 | Phospho-NFKB1 (S927) Antibody | Human,Mouse | WB, IHC, IF, ELISA |
| CSB-PA003430 | NFKB1 Antibody | Human | WB, IHC, IP, ELISA |
| CSB-PA003431 | NFKB1 Antibody | Human,Mouse | WB, IHC, IF, ELISA |
| CSB-PA003434 | NFKB1 Antibody | Human,Mouse | WB, IHC, IF, ELISA |
| CSB-PA004763 | NFKB1 Antibody | Human | WB, ELISA |
| CSB-PA020084 | Phospho-NFKB1 (S337) Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA020085 | NFKB1 Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA020086 | NFKB1 Antibody | Human,Mouse,Rat | IHC, ELISA |
| CSB-PA020090 | NFKB1 Antibody | Human | WB, IHC, ELISA |
| CSB-PA020096 | NFKB1 Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA259078 | NFKB1 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA546304 | NFKB1 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA441503 | NFKB1 Antibody | Human,Mouse,Rat | ELISA,WB |
NFKB1 Proteins
NFKB1 Proteins for Gallus gallus (Chicken)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP015759CH CSB-EP015759CH CSB-BP015759CH CSB-MP015759CH CSB-EP015759CH-B |
Recombinant Chicken Nuclear factor NF-kappa-B p105 subunit (NFKB1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NFKB1 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP015759HU1 CSB-BP015759HU1 CSB-MP015759HU1 CSB-EP015759HU1-B |
Recombinant Human Nuclear factor NF-kappa-B p105 subunit (NFKB1), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-RP103544h | Recombinant Human Nuclear factor NF-kappa-B p105 subunit (NFKB1) | E.coli |
| CSB-EP015759HU | Recombinant Human Nuclear factor NF-kappa-B p105 subunit (NFKB1) | E.coli |
| CSB-EP015759HU1 | Recombinant Human Nuclear factor NF-kappa-B p105 subunit (NFKB1), partial | E.coli |
NFKB1 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP015759MO CSB-EP015759MO CSB-BP015759MO CSB-MP015759MO CSB-EP015759MO-B |
Recombinant Mouse Nuclear factor NF-kappa-B p105 subunit (Nfkb1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NFKB1 Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP723572RA CSB-EP723572RA CSB-BP723572RA CSB-MP723572RA CSB-EP723572RA-B |
Recombinant Rat Nuclear factor NF-kappa-B p105 subunit (Nfkb1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NFKB1 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP739094DO CSB-EP739094DO CSB-BP739094DO CSB-MP739094DO CSB-EP739094DO-B |
Recombinant Dog Nuclear factor NF-kappa-B p105 subunit (NFKB1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NFKB1 ELISA Kit
NFKB1 ELISA Kit for Homo sapiens (Human)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E12107h | Human Nuclear factor-kappa B,NF-κB ELISA Kit | serum, plasma, tissue homogenates, cell lysates | 0.078 ng/mL |
NFKB1 ELISA Kit for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E12108m | Mouse Nuclear factor-kappa B,NF-κB ELISA Kit | serum, plasma, cell culture supernates | 0.078 ng/mL |
NFKB1 ELISA Kit for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E13148r | Rat Nuclear factor-kappa B(NF-κB) ELISA Kit |
