NOS3
NOS3，即一氧化氮合酶3，别名NOS III、NOS type III、NOS3。它是一种由NOS3基因编码的蛋白质，属于一氧化氮合酶家族成员之一。NOS3主要在血管内皮细胞中表达，对血管舒张和血液流动的调节具有重要作用。NOS3的作用机制是通过催化L-精氨酸的氧化反应，生成一氧化氮（NO）和L-瓜氨酸。一氧化氮是一种关键的血管舒张因子，能够激活鸟苷酸环化酶，增加cGMP水平，从而诱导血管平滑肌细胞的松弛。此外，NOS3生成的NO还参与了血小板聚集、白细胞黏附以及血管新生等生理过程。NOS3不仅参与了血管内皮的保护作用，还与多种疾病的发生发展密切相关。例如，NOS3的多态性与冠状动脉痉挛的易感性有关，其功能受损可能导致高血压等心血管疾病。此外，NOS3在肿瘤的发展和转移中也扮演着重要角色，其表达水平的变化可能影响肿瘤血管生成和肿瘤细胞的侵袭性。因此，NOS3是心血管疾病和肿瘤研究中的一个重要靶点。
热销产品
NOS3 Monoclonal Antibody (CSB-MA000326)
验证数据
Western blot analysis of Rat Heart Tissue, diluted at 1:1000.
NOS3 Antibodies
NOS3 for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA16579A0Rb | Nos3 Antibody | Rat | ELISA |
| CSB-PA16579C0Rb | Nos3 Antibody, FITC conjugated | Rat | |
| CSB-PA16579B0Rb | Nos3 Antibody, HRP conjugated | Rat | ELISA |
NOS3 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA279955 | Phospho-NOS3 (Ser1177) Antibody | Human,Mouse,Rat | ELISA,IHC,IF |
| CSB-PA043009 | NOS3 (Ab-1177) Antibody | Human,Mouse,Rat | ELISA,WB,IF |
| CSB-PA064019 | NOS3 (Ab-495) Antibody | Human,Mouse,Rat | ELISA,IF |
| CSB-PA921078 | Phospho-NOS3 (Ser615) Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA000659 | Phospho-NOS3 (S1177) Antibody | Human,Mouse,Rat | WB, IF, ELISA |
| CSB-PA003466 | NOS3 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA003467 | NOS3 Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA020134 | Phospho-NOS3 (T494) Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA020135 | Phospho-NOS3 (S615) Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA020136 | NOS3 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA020137 | NOS3 Antibody | Human,Mouse,Rat | WB, IF, ELISA |
NOS3 for H, M, R
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-MA000326 | NOS3 Monoclonal Antibody | Human,Mouse,Rat | ELISA,WB |
NOS3 Proteins
NOS3 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP015946MO CSB-EP015946MO CSB-BP015946MO CSB-MP015946MO CSB-EP015946MO-B |
Recombinant Mouse Nitric oxide synthase, endothelial (Nos3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NOS3 Proteins for Ovis aries (Sheep)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP015946SH CSB-EP015946SH CSB-BP015946SH CSB-MP015946SH CSB-EP015946SH-B |
Recombinant Sheep Nitric oxide synthase, endothelial (NOS3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NOS3 Proteins for Cavia porcellus (Guinea pig)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP015946GU CSB-EP015946GU CSB-BP015946GU CSB-MP015946GU CSB-EP015946GU-B |
Recombinant Guinea pig Nitric oxide synthase, endothelial (NOS3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NOS3 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP015946HU CSB-EP015946HU CSB-BP015946HU CSB-MP015946HU CSB-EP015946HU-B |
Recombinant Human Nitric oxide synthase, endothelial (NOS3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NOS3 Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP015946BO CSB-EP015946BO CSB-BP015946BO CSB-MP015946BO CSB-EP015946BO-B |
Recombinant Bovine Nitric oxide synthase, endothelial (NOS3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NOS3 Proteins for Sus scrofa (Pig)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP637927PI CSB-EP637927PI CSB-BP637927PI CSB-MP637927PI CSB-EP637927PI-B |
Recombinant Pig Nitric oxide synthase, endothelial (NOS3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NOS3 Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP733830RA CSB-EP733830RA CSB-BP733830RA CSB-MP733830RA CSB-EP733830RA-B |
Recombinant Rat Nitric oxide synthase, endothelial (Nos3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-RP165794r(A3) | Recombinant Rat Nitric oxide synthase, endothelial (Nos3), partial | E.coli |
NOS3 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP880009DO CSB-EP880009DO CSB-BP880009DO CSB-MP880009DO CSB-EP880009DO-B |
Recombinant Dog Nitric oxide synthase, endothelial (NOS3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NOS3 ELISA Kit
NOS3 ELISA Kit for Homo sapiens (Human)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E08322h | Human Endothelial nitric oxide synthase,eNOS ELISA Kit | serum, plasma, cell culture supernates, tissue homogenates | 0.27 IU/mL |
NOS3 ELISA Kit for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E08324m | Mouse Endothelial nitric oxide synthase,eNOS ELISA Kit | serum, plasma, tissue homogenates | 0.078 IU/mL |
NOS3 ELISA Kit for Sus scrofa (Pig)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E08574p | Pig Endothelial nitric oxide synthase,eNOS ELISA Kit | serum, plasma, tissue homogenates, cell lysates | 0.78 IU/mL |
NOS3 ELISA Kit for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E08323r | Rat Endothelial nitric oxide synthase,eNOS/NOS3 ELISA Kit | serum, plasma, cell culture supernates, cell lysates | 3.9 μIU/mL |
