Your Good Partner in Biology Research

NRAS

NRAS,即神经母细胞瘤RAS病毒癌基因同源物。别名N-ras、NRAS1。NRAS基因编码一种GTP结合蛋白,在细胞信号传导中起着分子开关的作用。它通过与GTP或GDP结合来循环激活和失活状态,控制细胞生长、分化和凋亡。NRAS的作用机制涉及RAS/RAF/MEK/ERK信号通路的激活,该通路控制基因转录活动和细胞周期,与细胞增殖相关。NRAS基因突变可导致蛋白持续激活,从而促进肿瘤的发生和发展,如黑色素瘤、结直肠癌、非小细胞肺癌等。

热销产品

Recombinant Human GTPase NRas (NRAS) (CSB-EP016070HU)

验证数据

CSB-EP016070HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

NRAS Antibody (CSB-PA016070LA01HU)

验证数据

CSB-PA016070LA01HU

Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA016070LA01HU at dilution of 1:100

CSB-PA016070LA01HU

Immunofluorescent analysis of HepG2 cells using CSB-PA016070LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

NRAS Antibodies

NRAS for Homo sapiens (Human)

NRAS Proteins

NRAS Proteins for Cavia porcellus (Guinea pig)

NRAS Proteins for Mus musculus (Mouse)

NRAS Proteins for Homo sapiens (Human)

NRAS Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

NRAS Proteins for Sus scrofa (Pig)

NRAS Proteins for Gallus gallus (Chicken)

NRAS Proteins for Pongo abelii (Sumatran orangutan)

NRAS Proteins for Xenopus laevis (African clawed frog)

NRAS Proteins for Monodelphis domestica (Gray short-tailed opossum)