PIK3C3
PIK3C3，即磷脂酰肌醇3-激酶催化亚基3型，别名VPS34、Vps34、hVps34。PIK3C3是磷脂酰肌醇3-激酶（PI3K）家族的成员，能够磷酸化磷脂酰肌醇（PtdIns）生成磷脂酰肌醇3-磷酸（PI3P），这是自噬过程中的一个中心磷脂质。PIK3C3在早期内体到晚期内体的转运和细胞质分裂的调节中发挥作用，位于自溶酶体、晚期内体和中体。PIK3C3对于自噬的形成至关重要，自噬是细胞在环境变化时维持生存的机制，也帮助肿瘤细胞抵抗代谢应激和癌症治疗。PIK3C3通过不依赖自噬的机制诱导肿瘤细胞的转化和增强肿瘤细胞的增殖、生长和侵袭。PIK3C3在多种人类肿瘤中的表达模式和在肿瘤发生中的潜在机制，以及在癌症生物学、患者预后预测和癌症治疗中的意义被广泛研究。
热销产品
PIK3C3 Antibody (CSB-PA854108LA01HU)
验证数据
Western Blot
Positive WB detected in: Hela whole cell lysate
All lanes: PIK3C3 antibody at 3.4μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 102 kDa
Observed band size: 102 kDa
Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA854108LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA854108LA01HU at dilution of 1:100
PIK3C3 Antibodies
PIK3C3 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA017997GA01HU | PIK3C3 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA909570 | PIK3C3 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA381950 | PIK3C3 Antibody | Human,Mouse,Rat,Cow | WB,ELISA |
| CSB-PA854108LA01HU | PIK3C3 Antibody | Human | ELISA, WB, IHC |
| CSB-PA854108LB01HU | PIK3C3 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA854108LC01HU | PIK3C3 Antibody, FITC conjugated | Human | |
| CSB-PA854108LD01HU | PIK3C3 Antibody, Biotin conjugated | Human | ELISA |
PIK3C3 Proteins
PIK3C3 Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP017997RA CSB-EP017997RA CSB-BP017997RA CSB-MP017997RA CSB-EP017997RA-B |
Recombinant Rat Phosphatidylinositol 3-kinase catalytic subunit type 3 (Pik3c3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PIK3C3 Proteins for Sus scrofa (Pig)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP707708PI CSB-EP707708PI CSB-BP707708PI CSB-MP707708PI CSB-EP707708PI-B |
Recombinant Pig Phosphatidylinositol 3-kinase catalytic subunit type 3 (PIK3C3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PIK3C3 Proteins for Xenopus laevis (African clawed frog)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP731839XBE CSB-EP731839XBE CSB-BP731839XBE CSB-MP731839XBE CSB-EP731839XBE-B |
Recombinant Xenopus laevis Phosphatidylinositol 3-kinase catalytic subunit type 3 (pik3c3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PIK3C3 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP754257MO CSB-EP754257MO CSB-BP754257MO CSB-MP754257MO CSB-EP754257MO-B |
Recombinant Mouse Phosphatidylinositol 3-kinase catalytic subunit type 3 (Pik3c3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PIK3C3 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP854108HU CSB-EP854108HU CSB-BP854108HU CSB-MP854108HU CSB-EP854108HU-B |
Recombinant Human Phosphatidylinositol 3-kinase catalytic subunit type 3 (PIK3C3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
