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SLC1A2

SLC1A2,即溶质载体家族1成员2,别名EAAT2、GLT-1等。它是一种由SLC1A2基因编码的跨膜蛋白,主要在大脑神经元和胶质细胞中表达。SLC1A2的作用机制涉及介导细胞外谷氨酸的转运,将其带入细胞内,对维持中枢神经系统的谷氨酸稳态至关重要。SLC1A2参与了神经递质谷氨酸的再摄取过程,对调节神经兴奋性和抑制性平衡具有重要作用。SLC1A2的功能异常与多种神经系统疾病有关,如癫痫、神经退行性疾病、脑损伤等。

热销产品

SLC1A2 Recombinant Monoclonal Antibody (CSB-RA051685A0HU)

验证数据

CSB-RA051685A0HU

Western Blot
Positive WB detected in: U251 whole cell lysate
All lanes: EAAT2 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 62 kDa
Observed band size: 62 kDa

CSB-RA051685A0HU

Overlay Peak curve showing MCF-7 cells surface stained with CSB-RA051685A0HU (red line) at 1:50. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1µg/1*106cells) for 45min at 4℃. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4℃.Control antibody (green line) was rabbit IgG (1µg/1*106cells) used under the same conditions. Acquisition of >10,000 events was performed.

SLC1A2 Antibodies

SLC1A2 for Homo sapiens (Human)

SLC1A2 Proteins

SLC1A2 Proteins for Rattus norvegicus (Rat)

SLC1A2 Proteins for Homo sapiens (Human)

SLC1A2 Proteins for Mus musculus (Mouse)