SLC2A1
SLC2A1全称为葡萄糖转运蛋白1(GLUT1),是人体内分布最广的葡萄糖转运载体,在血脑屏障、红细胞和胎盘等组织中高表达。SLC2A1通过促进葡萄糖跨膜运输维持脑部能量供应,对中枢神经系统功能至关重要。GLUT1缺陷综合征是其最典型的遗传性疾病,患者因转运功能障碍出现婴儿期癫痫、运动障碍和智力发育迟缓,临床通过脑脊液葡萄糖检测结合基因筛查确诊,生酮饮食替代供能是目前主要干预手段。胶质母细胞瘤、乳腺癌等恶性肿瘤中GLUT1常异常高表达,与肿瘤代谢重编程密切相关,这使得SLC2A1成为抗癌药物开发的重要靶点。例如小分子抑制剂BAY-876已在临床前研究中显示出阻断肿瘤葡萄糖摄取的效果。研究人员正探索通过调控GLUT1活性改善糖尿病并发症及阿尔茨海默病能量代谢障碍的新策略。
热销产品
验证数据

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
SLC2A1 Recombinant Monoclonal Antibody (CSB-RA297401A0HU)
验证数据

IHC image of CSB-RA297401A0HU diluted at 1:100 and staining in paraffin-embedded human cervical cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

IHC image of CSB-RA297401A0HU diluted at 1:100 and staining in paraffin-embedded human lung cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
SLC2A1 Antibodies
SLC2A1 for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA021546GA01HU | SLC2A1 Antibody | Human,Mouse,Rat | ELISA,WB,IF |
CSB-PA021546ESR2HU | SLC2A1 Antibody | Human, Mouse | ELISA, WB, IHC |
CSB-PA258056 | SLC2A1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA002728 | SLC2A1 Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA630217 | SLC2A1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA547464 | SLC2A1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
CSB-RA297401A0HU | SLC2A1 Recombinant Monoclonal Antibody | Human | ELISA, IHC |
SLC2A1 Proteins
SLC2A1 Proteins for Ovis aries (Sheep)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP021546SH CSB-EP021546SH CSB-BP021546SH CSB-MP021546SH CSB-EP021546SH-B |
Recombinant Sheep Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SLC2A1 Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP021546HU CSB-BP021546HU CSB-MP021546HU CSB-EP021546HU-B |
Recombinant Human Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP021546HU | Recombinant Human Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1), partial | E.coli |
CSB-CF021546HU(A4) | Recombinant Human Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1) | in vitro E.coli expression system |
SLC2A1 Proteins for Oryctolagus cuniculus (Rabbit)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP021546RB CSB-EP021546RB CSB-BP021546RB CSB-MP021546RB CSB-EP021546RB-B |
Recombinant Rabbit Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SLC2A1 Proteins for Sus scrofa (Pig)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP021546PI CSB-EP021546PI CSB-BP021546PI CSB-MP021546PI CSB-EP021546PI-B |
Recombinant Pig Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SLC2A1 Proteins for Mus musculus (Mouse)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP021546MO CSB-BP021546MO CSB-MP021546MO CSB-EP021546MO-B |
Recombinant Mouse Solute carrier family 2, facilitated glucose transporter member 1 (Slc2a1), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP021546MO | Recombinant Mouse Solute carrier family 2, facilitated glucose transporter member 1 (Slc2a1), partial | E.coli |
SLC2A1 Proteins for Bos taurus (Bovine)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP021546BO CSB-EP021546BO CSB-BP021546BO CSB-MP021546BO CSB-EP021546BO-B |
Recombinant Bovine Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SLC2A1 Proteins for Gallus gallus (Chicken)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP021546CH CSB-EP021546CH CSB-BP021546CH CSB-MP021546CH CSB-EP021546CH-B |
Recombinant Chicken Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SLC2A1 Proteins for Rattus norvegicus (Rat)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP319259RA CSB-BP319259RA CSB-MP319259RA CSB-EP319259RA-B |
Recombinant Rat Solute carrier family 2, facilitated glucose transporter member 1 (Slc2a1), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |