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SORT1

SORT1,即分拣蛋白1,别名Sortilin、NT3、Gp95、NTR3、LDLCQ6,是一种跨膜蛋白,属于VPS10相关sortilin蛋白家族。
SORT1在多个亚细胞区域发挥作用,包括高尔基体、内体、内质网和细胞膜,主要功能是作为分选受体,参与蛋白质的运输和代谢。SORT1可通过各种途径将蛋白质从高尔基体运输到溶酶体和内体,并且与多种蛋白质的内化和转运相关。
SORT1的表达水平可能影响心肌梗死的风险,并且与多种疾病相关,包括脂质代谢疾病、某些类型的癌症和神经退行性疾病。 SORT1在调节胆固醇代谢、促进神经细胞凋亡以及可能影响胰岛素响应等方面具有重要的生物学意义。

热销产品

SORT1 Antibody (CSB-PA859102LA01HU)

验证数据

CSB-PA859102LA01HU

IHC image of CSB-PA859102LA01HU diluted at 1:600 and staining in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

CSB-PA859102LA01HU

IHC image of CSB-PA859102LA01HU diluted at 1:600 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Human Sortilin(SORT1) ELISA kit (CSB-EL022412HU)

验证数据

CSB-EL022412HU 标准曲线

货号:CSB-EL022412HU

规格:96T/48T

灵敏度:11.72 pg/mL

检测范围:46.88 pg/mL-3000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

SORT1 Antibodies

SORT1 for Homo sapiens (Human)

SORT1 for Rattus norvegicus (Rat)

SORT1 Proteins

SORT1 Proteins for Rattus norvegicus (Rat)

SORT1 Proteins for Mus musculus (Mouse)

SORT1 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

SORT1 Proteins for Homo sapiens (Human)

SORT1 ELISA Kit

SORT1 ELISA Kit for Homo sapiens (Human)

SORT1 ELISA Kit for Mus musculus (Mouse)