Your Good Partner in Biology Research

TGFB3

转化生长因子-β3(TGF-β3)是调控胚胎发育和组织稳态的重要蛋白,在哺乳动物中也被简称为TGFB3。该蛋白属于转化生长因子超家族成员,与TGF-β1、TGF-β2具有相似结构但独特功能,尤其在心脏形态建成和腭板融合过程中起关键作用。TGFB3通过激活特定胞内分子网络,影响细胞增殖、分化及胞外基质沉积,异常表达可能引发先天性心脏病、腭裂等发育缺陷,并与肺纤维化、肿瘤转移等病理过程相关。近年有学者发现该蛋白在调控免疫微环境和抑制过度瘢痕形成方面具有潜力,相关抗体药物如GC1008已进入临床试验,用于特发性肺纤维化等疾病的干预。不过由于TGF-β家族成员功能的高度复杂性,针对TGF-β3的特异性靶向治疗仍需突破多重技术瓶颈。

热销产品

Recombinant Human Transforming growth factor beta-3 (TGFB3), partial (CSB-EP023449HU1)

验证数据

CSB-EP023449HU1

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

TGFB3 Antibody (CSB-PA023449LA01HU)

验证数据

CSB-PA023449LA01HU

Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA023449LA01HU at dilution of 1:100

CSB-PA023449LA01HU

Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA023449LA01HU at dilution of 1:100

Human Transforming Growth factor β3,TGF-β3 ELISA kit (CSB-E13738h)

验证数据

CSB-E13738h 标准曲线

货号:CSB-E13738h

规格:96T/48T

灵敏度:3.9 pg/mL

检测范围:15.6 pg/mL-1000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

TGFB3 Antibodies

TGFB3 for Homo sapiens (Human)

TGFB3 Proteins

TGFB3 Proteins for Homo sapiens (Human)

TGFB3 Proteins for Gallus gallus (Chicken)

TGFB3 Proteins for Sus scrofa (Pig)

TGFB3 Proteins for Mus musculus (Mouse)

TGFB3 ELISA Kit

TGFB3 ELISA Kit for Homo sapiens (Human)

TGFB3 ELISA Kit for Mus musculus (Mouse)