ZG16B
ZG16B，即酶原颗粒蛋白16同源物B。别名PAUF、JCLN2、HRPE773、PRO1567。ZG16B是一种含有一个p-棱镜结构的哺乳动物凝集素，具有调节细胞黏附、转移、凋亡、血管生成以及细胞与细胞间相互作用来识别病原体的能力。ZG16B的作用机制涉及激活多种信号通路，如CXCR4、β-catenin、TPL2/MEK/ERK、FAK/Scr等，促进肿瘤细胞的迁移和血管生成。ZG16B在多种肿瘤中异常表达，尤其是在胰腺癌中高表达，对肿瘤细胞的增殖、粘附、迁移、侵袭起着重要作用，使其成为具有潜力的肿瘤诊断生物标记物和治疗靶点。目前，已有多款针对ZG16B的抗体药物处于临床阶段，主要用于胰腺癌和卵巢癌治疗，显示了其在肿瘤治疗中的潜力和重要性。
热销产品
Recombinant Human Pancreatic adenocarcinoma up-regulated factor (ZG16B) (Active) (CSB-MP836195HU)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human ZG16B at 2 μg/ml can bind Anti-ZG16B recombinant antibody (CSB-RA836195MA1HU), the EC50 is 24.13-46.04 ng/mL.
The purity of ZG16B was greater than 95% as determined by SEC-HPLC
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis ZG16B at 2μg/mL can bind Anti-ZG16B recombinant antibody (CSB-RA836195MA1HU)， the EC50 is 20.15-28.98 ng/mL.
ZG16B Recombinant Monoclonal Antibody (CSB-RA836195MA1HU)
验证数据
The Binding Activity of Human ZG16B with Anti-ZG16B recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ZG16B (CSB-MP836195HU) at 2 μg/mL can bind Anti-ZG16B recombinant antibody, the EC50 is 24.13-46.04 ng/mL.
The Binding Activity of Macaca fascicularis ZG16B with Anti-ZG16B recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis ZG16B (CSB-MP4727MOV) at 2 μg/mL can bind Anti-ZG16B recombinant antibody , the EC50 is 20.15-28.98 ng/mL.
ZG16B Antibodies
ZG16B for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-RA836195MA1HU | ZG16B Recombinant Monoclonal Antibody | Human, Macaca fascicularis | ELISA |
ZG16B Proteins
ZG16B Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP836195HU | Recombinant Human Pancreatic adenocarcinoma up-regulated factor (ZG16B) | Yeast |
| CSB-EP836195HU | Recombinant Human Pancreatic adenocarcinoma up-regulated factor (ZG16B) | E.coli |
| CSB-BP836195HU CSB-EP836195HU-B |
Recombinant Human Pancreatic adenocarcinoma up-regulated factor (ZG16B) | Baculovirus In Vivo Biotinylation in E.coli |
| CSB-MP836195HU | Recombinant Human Pancreatic adenocarcinoma up-regulated factor (ZG16B) (Active) | Mammalian cell |
| CSB-MP836195HUd9 | Recombinant Human Pancreatic adenocarcinoma up-regulated factor (ZG16B) | Mammalian cell |
